Credits: 3 (3-0-0)

Prerequisites: CLL110

Overlaps with: BEN150, BBL431, BBL731

Description

Introduction to biopharmaceutical industry. Monod kinetics. Michaelis Menten kinetics. Introduction to the different bioprocessing unit operations utilized in production of biotech drugs - upstream, harvest, and downstream. Design, control and scale up of bioreactor. Introduction to analytical methods used for characterization of biotech products and processes (high performance liquid chromatography, mass spectrophotometry, capillary electrophoresis, near infrared spectroscopy, UV spectroscopy). Fundamentals and design of filtration and other membrane based separation techniques. Process chromatography - theory, practice, design and scale-up. Mixing, heat transfer and mass transfer in bioprocessing unit operations. Scale-up of filtration and chromatography unit operations utilized in bioprocessing: procedures, issues that frequently occur and possible solutions. Process design, control and optimization. Current topics in biopharmaceutical technology.

Prerequisite Tree

flowchart TD
CLL271-116[CLL271]
CLL271-116 --> CLL110-116[CLL110]

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