Credits: 3 (3-0-0)
Prerequisites: SBL100 and EC75 for UG students
Description
Tumor microenvironment; tumor heterogeneity - both inter and intra- tumoral heterogeneity; intrinsic and extrinsic factors influencing tumor heterogeneity; cancer cell plasticity – evolving theories of cancer sternness or tumor-initiation; cancer evolution - factors influencing this change and their impact on therapy; cancer metabolism - oncometabolites, metabolic exchange and metabolic circuit rewiring in different regions of tumors; metabolic symbiosis between cancer and stromal elements; microbiome influence on cancer (a new emerging hallmark of cancer); immuno-oncology - immunophenotyping during cancer, cancer mediated immune evasion and exhaustion and their impact on immunotherapy; cancer invasion and metastasis - epithelial to mesenchymal and mesenchymal to epithelial transition; metastatic dissemination mechanism and colonization/homing; modern tools in cancer biology – single cell sequencing, metabolomics, multi-omics; current approved drugs, combinatorial therapy, immunotherapy - and challenges ahead.
Prerequisite Tree
flowchart TD
SBL729-1543[SBL729]
SBL729-1543 --> SBL100-1543[SBL100]
SBL729-1543 --> EC75-1543[EC75]
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