Credits: 3 3-0-0)
Prerequisites: Pre-requisite(s): EC 75 and SBL100 for UG students
Description
Introduction to molecular motors and biological motor proteins, historical perspectives, basics principles and broad functions; Polymerization motors: actin, tubulin and intermediary filaments- their structure-function, dynamics – from in-vivo and in-vitro studies and regulation; Force generators: Myosins, dyneins and Kinesisn – their structure-function and reulation. Rotational motors – FoF1ATP synthase and bacterial flagella (structure and function). Eukaryotic Cilia/flagella; DNA helicase and polymerase; Viral assembly – with specific examples of bacteriophages and retroviruses; recent advance (research articles) on organelle transport; Nuclear motors; Molecular motors associated with disease – with emphasis on myosin, dynein and kinesin; Methodologies used to study biological motor proteins; Biological motors in futuristic design.
Prerequisite Tree
flowchart TD
SBL726-1537[SBL726]
SBL726-1537 --> SBL100-1537[SBL100]
SBL726-1537 --> EC75-1537[EC75]
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