Credits: 4 (3-0-2)
Prerequisites: EC 75
Description
Theoretical Part: Basic Introduction to mechano-biology, Concept of Length Scale, Mechanical Forces, Mass, Stiffness and Damping of Proteins, Thermal Forces and Diffusion, Chemical Forces, Polymer Mechanics. Intracellular Mechanics: Structures of Cytoskeleton Filaments, Dynamics of Cell Filaments, Molecular motors, Introduction to Entropic Elasticity and Persistence Length, Force Generation by Cytoskeleton Filaments. Extracellular Mechanics: The Extracellular matrix (ECM), Cell-ECM Interactions, Cell Migration, Forces and Adhesion. Tissue Mechanics: Cell-cell Assemblies, Tissue Material Behavior, Introduction to Linear Viscoelasticity, Concept of Constitutive Modeling. Experimental Part: Different Experimental Methods for Probing Cell Mechanical Properties. Intro to indentation, Aspiration, Twezeer, Nano patterened platform based techniques etc.
Prerequisite Tree
flowchart TD
APL740-60[APL740]
APL740-60 --> EC75-60[EC75]
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