Credits: 1 (1-0-0)
Prerequisites: EC 75 with SBL100/ BBL131
Description
Overview of neuronal physiology; Ion channels and receptors of excitable cell membrane; Ion channel properties: Permeability, Selectivity, Gating and Rectification; Nernst-Plank and Goldman- Hodgkin-Katz equations; Classification of ion channels and receptors; Structure and function studies of ion channels and receptors: voltage-gated Na+ and K+ channels, ligand-gated acetylcholine receptor channel, mechano-gated mscL and Piezo channels; Allosteric modulation of ion channels: theories and application; Ion channel and receptor pharmacology; Methods to study ion channels and receptors: Patch-Clamp, planar-bilayer, crystallography and Cryo-EM studies; Simulation of single channel activity and macroscopic currents from kinetic modeling.
Prerequisite Tree
flowchart TD
SBV892-1546[SBV892]
SBV892-1546 --- Or1547[Any one of]:::empty
Or1547 -.-> SBL100-1548[SBL100]
Or1547 -.-> BBL131-1549[BBL131]
SBV892-1546 --> EC75-1546[EC75]
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