Credits: 4.5 (3-0-3)
Description
Historical development and essentials of Mendelian genetics. Chromosomal theory of inheritance. Evolution and development of molecular biology. DNA model and classes. Organization of eukaryotic chromosome – the chromatin structure. Gene structure and Genome. Transposon. Genetic Information and its perpetuation – DNA replication, damage and repair. Telomere and Aging. Transcription, translation. Molecular biology of bacteriophage lamda. Gene exchange in bacteria. Gene regulation in prokaryotes. The operon model – lac, ara, trp operons and gene regulation. Gene Regulation in Eukaryotes. DNA Methylation and Genomic Imprinting.
Laboratory: Isolation of genomic and plasmid DNA, Agarose Gel Electrophoresis of DNA, Restriction digestion of DNA, RNA isolation, Primer design, PCR, RT-PCR, Competent cell preparation and Transformation, Gene Induction.
Prerequisite Tree
flowchart TD
BBL231-71[BBL231]
BBL231-71 --> BBL132-71[BBL132]
BBL231-71 --> BBL131-71[BBL131]
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