Credits: 1 (1-0-0)
Prerequisites: Pre-requisite(s): EC100 and SBL100 for UG students
Description
Angiogenesis and vasculogenesis; the lymphatic system; introduction to blood vessels: types, structure, and composition. Blood vessel components – endothelial cells, pericytes, and vascular smooth muscle cells; vascular endothelial growth factor (VEGF) biology – its role in angiogenesis and vascular permeability; basic fibroblast growth factor biology; VEGF and FGF receptors, tyrosine kinase signaling and activation; angiogenesis and immune system; tumor angiogenesis - Judah Folkman hypothesis, discovery and how the field of vascular biology in cancer has evolved over the years; tumor vasculature and perfusion; antiangiogenesis as a current therapeutic strategy – where we stand?; blood vessel inhibition vs normalization; vessel co-option and vascular mimicry; atherogenesis; anti-angiogenic therapy in age- related macular degeneration; Vascular aging; different in vitro, in vivo, and ex vivo models to study vascular biology.
Prerequisite Tree
flowchart TD
SBV897-1556[SBV897]
SBV897-1556 --> SBL100-1556[SBL100]
SBV897-1556 --> EC100-1556[EC100]
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